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1

Frequency of behavioral symptoms characterizes agitation in Alzheimer's disease

Rochelle E. Tractenberg, Anthony Gamst, Myron F. Weiner, Elisabeth Koss, Ronald G. Thomas, Linda Teri, Leon Thal

Journal:

International Journal of Geriatric Psychiatry

Année:

2001

Langue:

english

Fichier:

PDF, 68 KB

english, 2001

2

Current Concepts in Mild Cognitive Impairment

Petersen, Ronald C., Doody, Rachelle, Kurz, Alexander, Mohs, Richard C., Morris, John C., Rabins, Peter V., Ritchie, Karen, Rossor, Martin, Thal, Leon, Winblad, Bengt

Journal:

Archives of Neurology

Année:

2001

Langue:

english

Fichier:

PDF, 113 KB

english, 2001

3

Comparison of the serial position effect in very mild Alzheimer's disease, mild Alzheimer's disease, and amnesia associated with electroconvulsive therapy

BAYLEY, PETER J., SALMON, DAVID P., BONDI, MARK W., BUI, BARBARA K., OLICHNEY, JOHN, DELIS, DEAN C., THOMAS, RONALD G., THAL, LEON J.

Journal:

Journal of the International Neuropsychological Society

Année:

2000

Langue:

english

Fichier:

PDF, 132 KB

english, 2000

4

Mnemonic Deficits in Animals Depend upon the Degree of Cholinergic Deficit and Task Complexity

Donald P. Pizzo, Leon J. Thal, Jürgen Winkler

Journal:

Experimental Neurology

Année:

2002

Langue:

english

Fichier:

PDF, 323 KB

english, 2002

5

Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis

Ad J. Dekker, Anne M. Fagan, Fred H. Gage, Leon J. Thal

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 733 KB

english, 1994

6

Nucleus basalis lesions fail to induce senile plaques in the rat

Leon J. Thal, Ronald J. Mandel, Robert D. Terry, Gyorgy Buzsaki, Fred H. Gage

Journal:

Experimental Neurology

Année:

1990

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1990

7

Lack of long-term effects after β-amyloid protein injections in rat brain

Jürgen Winkler, Don J. Connor, Sally A. Frautschy, Christian Behl, Jerene J. Waite, Greg M. Cole, Leon J. Thal

Journal:

Neurobiology of Aging

Année:

1994

Langue:

english

Fichier:

PDF, 1021 KB

english, 1994

8

Mutations in Mitochondrial Cytochrome c Oxidase Genes Segregate with Late-Onset Alzheimer Disease

Robert E. Davis, Scott Miller, Corinna Herrnstadt, Soumitra S. Ghosh, Eoin Fahy, Leslie A. Shinobu, Douglas Galasko, Leon J. Thal, M. Flint Beal, Neil Howell and W. Davis Parker

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1997

9

Clinical Dementia Rating training and reliability in multicenter studies: The Alzheimer's Disease Cooperative Study experience

Morris, J. C., Ernesto, C., Schafer, K., Coats, M., Leon, S., Sano, M., Thal, L. J., Woodbury, P.

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 391 KB

english, 1997

10

[Progress in Brain Research] Cholinergic Mechanisms: from Molecular Biology to Clinical Significance Volume 109 || Chapter 29 Cholinomimetic treatment of Alzheimer's disease

Année:

1996

Langue:

english

Fichier:

PDF, 917 KB

english, 1996

11

Analysis of longitudinal data in an Alzheimer's disease clinical trial

Ronald G. Thomas, Julie D. Berg, Mary Sano, Leon Thal

Journal:

Statistics in Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 128 KB

english, 2000

12

Treatment of myoclonus with l-5-hydroxytryptophan and carbidopa: Clinical, electrophusiological, and biochemical observations

Dr. Leon J. Thal, Nansie S. Sharpless, Leslie Wolfson, Robert Katzman

Journal:

Annals of Neurology

Année:

1980

Langue:

english

Fichier:

PDF, 619 KB

english, 1980

13

Choline chloride in Alzheimer disease

Leon J. Thal, Wilma Rosen, Nansie S. Sharpless, Howard Crystal

Journal:

Annals of Neurology

Année:

1981

Langue:

english

Fichier:

PDF, 126 KB

english, 1981

14

Comparison of rate of annual change of mental status score in four independent studies of patients with Alzheimer's disease

Dr. Robert Katzman, Theodore Brown, Leon J. Thal, Paula A. Fuld, Miriam Aronson, Nelson Butters, Melville R. Klauber, Wigbert Wiederholt, Marchy Pay, Xiong Renbing, Dr. Wee Lock Ooi, Richard Hofstette

Journal:

Annals of Neurology

Année:

1988

Langue:

english

Fichier:

PDF, 579 KB

english, 1988

15

The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease

Xiaohua Chen, Yu Xia, Michael Alford, Richard DeTeresa, Lawrence Hansen, Melville R. Klauber, Robert Katzman, Leon Thal, Eliezer Masliah, Dr Tsunao Saitoh

Journal:

Annals of Neurology

Année:

1995

Langue:

english

Fichier:

PDF, 667 KB

english, 1995

16

Reversible schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor

Jürgen Winkler, Gilbert A. Ramirez, H. Georg Kuhn, Daniel A. Peterson, Patricia A. Day-Lollini, Gregory R. Stewart, Mark H. Tuszynski, Fred H. Gage, Dr Leon J. Thal

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1997

17

Genetic evidence for the involvement of τ in progressive supranuclear palsy

Chris Conrad, Athena Andreadis, John Q. Trojanowski, Dennis W. Dickson, David Kang, Xiaohua Chen, Wigbert Wiederholt, Larry Hansen, Dr Eliezer Masliah, Leon J. Thal, Robert Katzman, Yu Xia, Tsunao Sai

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 538 KB

english, 1997

18

Early-onset Alzheimer's disease with a presenilin-1 mutation at the site corresponding to the volga German presenilin-2 mutation

Richard Crook, Ronald Ellis, Megan Shanks, Leon J. Thal, Jordi Perez-Tur, Matt Baker, Mike Hutton, Tuomas Haltia, Dr. John Hardy, Douglas Galasko

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 491 KB

english, 1997

19

Drug treatment of alzheimer's disease

Journal:

Drug Development Research

Année:

1988

Langue:

english

Fichier:

PDF, 81 KB

english, 1988

20

Alzheimer's disease: Tacrine and tacrine metabolite concentrations in plasma and cognitive change

Kenneth L. Davis, Ren-Kui Yang, Michael Davidson, Richard C. Mohs, Theresa M. Ryan, James Schmeidler, Peter J. Knott, Leon J. Thal, Elkan R. Gamzu

Journal:

Drug Development Research

Année:

1995

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1995

21

APOE genotype predicts depression in women with Alzheimer's disease: a retrospective study

Lisa Delano-Wood, Wes S. Houston, Jennifer A. Emond, Natalie L. Marchant, David P. Salmon, Dilip V. Jeste, Leon J. Thal, Mark W. Bondi

Journal:

International Journal of Geriatric Psychiatry

Année:

2008

Langue:

english

Fichier:

PDF, 89 KB

english, 2008

22

How to define treatment success using cholinesterase inhibitors

Journal:

International Journal of Geriatric Psychiatry

Année:

2002

Langue:

english

Fichier:

PDF, 40 KB

english, 2002

23

3D comparison of low, intermediate, and advanced hippocampal atrophy in MCI

Liana G. Apostolova, Paul M. Thompson, Amity E. Green, Kristy S. Hwang, Charleen Zoumalan, Clifford R. Jack Jr, Danielle J. Harvey, Ronald C. Petersen, Leon J. Thal, Paul S. Aisen, Arthur W. Toga, Jef

Journal:

Human Brain Mapping

Année:

2010

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2010

24

3D comparison of low, intermediate, and advanced hippocampal atrophy in MCI

Liana G. Apostolova, Paul M. Thompson, Amity E. Green, Kristy S. Hwang, Charleen Zoumalan, Clifford R. Jack Jr, Danielle J. Harvey, Ronald C. Petersen, Leon J. Thal, Paul S. Aisen, Arthur W. Toga, Jef

Journal:

Human Brain Mapping

Année:

2010

Langue:

english

Fichier:

PDF, 42 KB

english, 2010

25

The role of cholinergic projections from the nucleus basalis in memory

A.D. J.A.M. Dekker, Donald J. Connor, Leon J. Thal

Journal:

Neuroscience & Biobehavioral Reviews

Année:

1991

Langue:

english

Fichier:

PDF, 1.96 MB

english, 1991

26

Intraparenchymal infusions of 192 IgG-saporin: development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei

Donald P Pizzo, Jerene J Waite, Leon J Thal, Jürgen Winkler

Journal:

Journal of Neuroscience Methods

Année:

1999

Langue:

english

Fichier:

PDF, 405 KB

english, 1999

27

The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease

Rochelle E. Tractenberg, Clifford M. Singer, Jeffrey L. Cummings, Leon J. Thal

Journal:

Journal of Sleep Research

Année:

2003

Langue:

english

Fichier:

PDF, 111 KB

english, 2003

28

Expression Pattern of Synucleins (Non-Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α-Synuclein) During Murine Brain Development

Leigh J. Hsu, Margaret Mallory, Yu Xia, Isaac Veinbergs, Makoto Hashimoto, Makoto Yoshimoto, Leon J. Thal, Tsunao Saitoh, Eliezer Masliah

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1.31 MB

english, 1998

29

Apolipoprotein E levels in cerebrospinal fluid and the effects ofABCA1polymorphisms

Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate, David M Holtzman

Journal:

Molecular Neurodegeneration

Année:

2007

Langue:

english

Fichier:

PDF, 300 KB

english, 2007

30

Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: Studies with chronic clozapine and haloperidol

Thomas. F. Seeger, Leon Thal, Eliot L. Gardner

Journal:

Psychopharmacology

Année:

1982

Langue:

english

Fichier:

PDF, 826 KB

english, 1982

31

Independent effects of cholinergic and serotonergic lesions on acetylcholine and serotonin release in the neocortex of the rat

Ad J. Dekker, Leon J. Thal

Journal:

Neurochemical Research

Année:

1993

Langue:

english

Fichier:

PDF, 715 KB

english, 1993

32

Cholinergic strategies for Alzheimer’s disease

J. Winkler, Leon J. Thal, Fred H. Gage, Lisa J. Fisher

Journal:

Journal of Molecular Medicine

Année:

1998

Langue:

english

Fichier:

PDF, 286 KB

english, 1998

33

Does the mitochondrial genome play a role in the etiology of Alzheimer’s disease?

Joanna L. Elson, Corinna Herrnstadt, Gwen Preston, Leon Thal, Christopher M. Morris, J. A. Edwardson, M. Flint Beal, Douglass M. Turnbull, Neil Howell

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 312 KB

english, 2006

34

Feasibility of Multi-site Clinical Structural Neuroimaging Studies of Aging Using Legacy Data

Christine Fennema-Notestine, Anthony C. Gamst, Brian T. Quinn, Jenni Pacheco, Terry L. Jernigan, Leon Thal, Randy Buckner, Ron Killiany, Deborah Blacker, Anders M. Dale, Bruce Fischl, Brad Dickerson,

Journal:

Neuroinformatics

Année:

2007

Langue:

english

Fichier:

PDF, 347 KB

english, 2007

35

Nerve growth factor gene therapy for alzheimer’s disease

Mark H. Tuszynski, Leon Thal, Hoi-Sang U, Mary Margaret Pay, Armin Blesch, James Conner, H. Lee Vahlsing

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 43 KB

english, 2002

36

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

Seubert, Peter, Oltersdorf, Tilman, Lee, Michael G., Barbour, Robin, Blomquist, Cheryl, Davis, David L., Bryant, Karin, Fritz, Lawrence C., Galasko, Douglas, Thal, Leon J.

Journal:

Année:

1993

Fichier:

PDF, 505 KB

1993

37

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

Vahlsing, H Lee, Ho, Gilbert, Tuszynski, Mark H, Thal, Leon, Pay, Mary, Salmon, David P, U, Hoi Sang, Bakay, Roy, Patel, Piyush, Blesch, Armin

Journal:

Nature Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 651 KB

english, 2005

38

Habituation and retention of the head-shake response: Lack of impairment by nucleus basalis magnocellularis lesions

Carl P.J. Dokla, Sean C. Parker, Leon J. Thal

Journal:

Pharmacology Biochemistry and Behavior

Année:

1990

Langue:

english

Fichier:

PDF, 468 KB

english, 1990

39

P44 Implementation of multicenter clinical trials: The Alzheimer's Disease Cooperative Study protocol implementation manual

Kimberly Schafer, Leon Thal, Jacqueline Bochenek, Mary Sano, Michael Grundman, Peter Woodbury, Melville Klauber, Paul Aisen

Journal:

Controlled Clinical Trials

Année:

1995

Langue:

english

Fichier:

PDF, 68 KB

english, 1995

40

P63 Informed consent issues when including genetic testing in clinical trials

Kimberly Schafer, Ronald Thomas, Douglas Galasko, John C. Morris, Peter Whitehouse, Jacqueline Bochenek, Leon Thal

Journal:

Controlled Clinical Trials

Année:

1996

Langue:

english

Fichier:

PDF, 160 KB

english, 1996

41

Nerve growth factor promotes survival of new neurons in the adult hippocampus

Helena Frielingsdorf, Daniel R. Simpson, Leon J. Thal, Donald P. Pizzo

Journal:

Neurobiology of Disease

Année:

2007

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2007

42

Short-term and complete reversal of NGF effects in rats with lesions of the nucleus basalis magnocellularis

Jürgen Winkler, Ann E Power, Gilbert A Ramirez, Leon J Thal

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1998

43

Assessing Alzheimer's disease patients with the Cohen-Mansfield Agitation Inventory: scoring and clinical implications

Myron F Weiner, Rochelle E Tractenberg, Shelia Jin, Anthony Gamst, Ronald G Thomas, Elisabeth Koss, Leon J Thal

Journal:

Journal of Psychiatric Research

Année:

2002

Langue:

english

Fichier:

PDF, 104 KB

english, 2002

44

A comparison of the Cohen-Mansfield agitation inventory with the cerad behavioral rating scale for dementia in community-dwelling persons with Alzheimers disease

Myron F Weiner, Elisabeth Koss, Marian Patterson, Shelia Jin, Linda Teri, Ron Thomas, Leon J Thal, Peter Whitehouse

Journal:

Journal of Psychiatric Research

Année:

1998

Langue:

english

Fichier:

PDF, 141 KB

english, 1998

45

Quantifying behavioral disturbance in Alzheimer's disease patients

Myron F. Weiner, Rochelle Tractenberg, Linda Teri, Rebecca Logsdon, Ronald G. Thomas, Anthony Gamst, Leon J. Thal

Journal:

Journal of Psychiatric Research

Année:

2000

Langue:

english

Fichier:

PDF, 104 KB

english, 2000

46

53 Power comparisons among different number of categories under ordered polytomous logistic regression model

Jong-Hyeon Jeong, Melville R. Klauber, Ronald G. Thomas, Michael Grundman, Leon J. Thal

Journal:

Controlled Clinical Trials

Année:

1997

Langue:

english

Fichier:

PDF, 76 KB

english, 1997

47

Power calculation for randomized start design

Yin M. Kean, Ronald G. Thomas, Leon J. Thal

Journal:

Controlled Clinical Trials

Année:

1998

Langue:

english

Fichier:

PDF, 69 KB

english, 1998

48

Dynamic measurement scale development for clinical trials in targeted populations

Shelia Jin, Ronald G. Thomas, Douglas Galasko, Leon J. Thal

Journal:

Controlled Clinical Trials

Année:

1998

Langue:

english

Fichier:

PDF, 77 KB

english, 1998

49

Measuring cognitive progression in Alzheimer's disease

Julie D. Berg, Ronald G. Thomas, Leon J. Thal, Mary Sano

Journal:

Controlled Clinical Trials

Année:

1998

Langue:

english

Fichier:

PDF, 148 KB

english, 1998

50

Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis

Miguel A Pappolla, Mark A Smith, Tara Bryant-Thomas, Nicolas Bazan, Suzana Petanceska, George Perry, Leon J Thal, Mary Sano, Lorenzo M Refolo

Journal:

Free Radical Biology and Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 244 KB

english, 2002